Associate Director, Center for Applied Genomics, Childrens Hospital of Philadelphia
Greater Philadelphia Area
- Current
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- Assitant Professor (Tenure Track) at University of Pennsylvania School of Medicine
- Adjunct Assistant Professor at Scripps
- Associate Director, Center for Applied Genomics at The Childrens Hospital of Philadelphia
- Education
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- University of Aberdeen
- University of Aberdeen
- Connections
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25
connections
- Industry
- Research
- Websites
Struan Grant’s Summary
I have been conducting human genetics research for over 10 years. The highlights of my career are the discovery of the polymorphic Sp1 site in the COL1A1 gene and its association with osteoporosis, and the identification of variation in the TCF7L2 gene playing a role in more than 20 percent of type 2 diabetes cases. I have achieved these findings by working with key populations around the world that provide a unique insight into how to isolate human disease genes.
My current work continues to primarily focus on metabolic disease, with a specific focus on pediatrics. Utilizing high-throughput genotyping technology, my goals include isolating genes involved in childhood obesity and pediatric bone strength determination. Both of these phenotypes are known to be strongly determined by genetic factors; however, the isolation of genes in these complex phenotypes in adults has been impeded by interaction with strong environmental factors. Distillation of the genetic component in these complex traits should be easier to determine in children, where the relatively short period of their lifetime limits the impact of environmental exposure. Given the global prevalence of obesity and osteoporosis, prevention of these disorders and their serious complications must be addressed in order to reduce individual morbidity and the economic burden on society.
Struan Grant’s Specialties:
Genetics, genomics, diabetes, obesity, osteoporosis, genome wide association, bone, pediatrics
Struan Grant’s Experience
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Assitant Professor (Tenure Track)
University of Pennsylvania School of Medicine
(Hospital & Health Care industry)
2007 — Present (2 years )
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Adjunct Assistant Professor
Scripps
(Public Company; Hospital & Health Care industry)
November 2007 — Present (2 years 2 months)
Department of Molecular and Experimental Medicine
Division of Hematology and Genetics -
Associate Director, Center for Applied Genomics
The Childrens Hospital of Philadelphia
(Non-Profit; Hospital & Health Care industry)
July 2006 — Present (3 years 6 months)
Struan Grant’s Education
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University of Aberdeen
PhD , Genetics , 1992 — 1995
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University of Aberdeen
BSc , Genetics , 1987 — 1991
- Activities and Societies:
- Student Representative Council, Amnesty International
