Manager, Sequencing Operations: 454 and Viral at Broad Institute
Greater Boston Area
Manager, Sequencing Operations: 454 and Viral at Broad Institute
Greater Boston Area
Operations; Six Sigma; Genome sequencing; Project Management; Process design; Automation; A wide array of cell biology techniques.
(Non-Profit; Research industry)
March 2009 — Present (5 months)
The Sequencing Operations: 454 and Viral Team is responsible for process development and production activities for the Roche 454 Platform in addition to methods development for viral genome sequencing on both traditional and next-generation platforms.
(Educational Institution; Biotechnology industry)
November 2006 — March 2009 (2 years 5 months)
• Responsible for the management of a multi-disciplinary team (from lab assistant to PhD level) within the Genome Sequencing Platform, reporting to the Director of Operations.
• Provide scientific and technical expertise to collaborators in five countries as part of the Genome Resources in Dengue and HIV Elite Controllers projects.
• En route to generate sequence data for over 13,000 viral genomes, including HIV, HCV, Dengue and West Nile Virus.
(Educational Institution; 201-500 employees; Biotechnology industry)
July 2005 — November 2006 (1 year 5 months)
This position involved providing technical and scientific support to the Special Projects Group who undertake a variety of custom sequencing and molecular biology projects.
(Non-Profit; Hospital & Health Care industry)
May 2001 — June 2005 (4 years 2 months)
Cecil B. Day Laboratory for Neuromuscular Research
Project 1. To use microarray technology and functional genomics to examine gene expression and possible interacting gene networks in models of muscular dystrophy. This project resulted in the identification of two novel binding partners for our protein of interest.
Project 2. To investigate the role of the muscle protein dysferlin in mediating membrane repair.
Project 3. To develop a high-throughput screening (HTS) assay to identify small molecules that modulate the membrane repair response in normal and dystrophic muscle. A preliminary patent application has been filed with the US Patent Office for this novel drug screening assay that has application to the biology of muscle injury and repair including muscular dystrophy and exercise-induced injury.
Management Courses at Harvard Extension 2006 — 2009
- Operations Management (Spring 2009)
- Biotechnology Project Management
- Innovation, Entrepreneurship and Business Transformation
Ph.D. , Pharmacology , 1997 — 2001
B.Sc. , Pharmacology Major , 1993 — 1997
Teaching: - Guest Lecturer at Tufts University Dept of BioMedical Engineering (2007-present). Process Design and Optimization: - Six Sigma Black Belt awarded in 2007. - Patent Pending on high-throughput assay for drug discovery. Communications: - Editor of national quarterly newsletter for BioLink USA-Ireland (2004-2006). - Completed Graduate course on 'Creative Non-fiction Writing' at Harvard Extension School.