Physicist, Sordina S.p.A.
- Roma, Italia
- Medical Devices
Alessia Ciccotelli's Overview
- Physicist LIAC Technical Division at Sordina
Alessia Ciccotelli's Experience
Physicist LIAC Technical Division
Società privata non quotata; 51-200 dipendenti; Settore: Medical Devices
luglio 2009 – Presente (5 anni 3 mesi) Roma, Italia
IORT Dedicated Accelerator Application Specialist
Acceptance Test and Training
Alessia Ciccotelli's Patents
Alessia Ciccotelli's Skills & Expertise
- Technical Documentation
- User Acceptance Testing
- Medical Physics
- Monte Carlo Simulation
- Scientific Writing
Alessia Ciccotelli's Publications
Autori: Alessia Ciccotelli, Marco D'Andrea, Giuseppe Felici, Antonella Soriani, giuseppe iaccarino, marcello benassi, Lidia Strigari, Luca Bellesi
- Med Phys.
- ottobre 2012
The aim of this study was to design and build a prototype beam shaper to be used on a dedicated mobile accelerator that protects organs at risk within the radiation field and conforms the beam to the target geometry during intraoperative electron radiotherapy (IOERT). A dosimetric characterization of the beam shaper device was performed based on Monte Carlo (MC) simulations, as well as experimental data, at different energies, field sizes, and source to skin distances.Methods: A mobile light intraoperative accelerator (LIAC(®), Sordina, Italy) was used. The design of the beam shaper prototype was based on MC simulations (BEAMnrc∕OMEGA and DOSXYZnrc code) for a selection of materials and thicknesses, as well as for dosimetric characterization. Percentage depth dose (PDD) and profile measurements were performed using a p-type silicon diode and a commercial water phantom, while output factors were measured using a PinPoint ion chamber in a PMMA phantom. The output factors (OFs) were determined using different geometrical set-ups and energies.Results: The beam shaper prototype consists of four blades sliding alongside each other and mounted on a special support at the end of the 10 cm diameter PMMA circular applicator. Each blade is made of an upper layer of 2.6 cm of Teflon(®) and a lower layer of 8 mm of stainless steel. All rectangles inscribed in a 5 cm diameter can be achieved in addition to any "squircle-shaped" field. When one side of the rectangular field is held constant and the second side is reduced, both R(50) and R(max) move towards the phantom surface. MC simulation showed an excellent agreement with experimental data (<2%).Conclusions: The beam shaper device is able to provide square∕rectangular∕squircle fields with adequate dose homogeneity for mobile dedicated accelerators, thus allowing conformal treatment with IOERT.
Autori: Alessia Ciccotelli, Giuseppe Felici, giuseppe iaccarino, marcello benassi, Lidia Strigari, Luca Bellesi, Antonella Soriani, Marco D'Andrea
- Phys Med Biol.
- 21 luglio 2011
The aim of this study was to investigate the dosimetric characteristics of the electron beams generated by the light intraoperative accelerator, Liac® (SORDINA, Italy), using Monte Carlo (MC) calculations. Moreover we investigated the possibility of characterizing the Liac® dosimetry with a minimal set of dosimetric data. In fact accelerator commissioning requires measurements of both percentage depth doses (PDDs) and off-axis profiles for all the possible combinations of energy, applicator diameter and bevelled angle. The Liac® geometry and water phantom were simulated in a typical measurement setup, using the MC code EGSnrc/BEAMnrc. A simulated annealing optimization algorithm was used in order to find the optimal non-monoenergetic spectrum of the initial electron beam that minimizes the differences between calculated and measured PDDs. We have concluded that, for each investigated nominal energy beam, only the PDDs of applicators with diameters of 30, 70 and 100 mm and the PDD without an applicator were needed to find the optimal spectra. Finally, the output factors of the entire set of applicator diameters/bevelled angles were calculated. The differences between calculated and experimental output factors were better than 2%, with the exception of the smallest applicator which gave differences between 3% and 4% for all energies. The code turned out to be useful for checking the experimental data from various Liac® beams and will be the basis for developing a tool based on MC simulation to support the medical physicist in the commissioning phase.
Alessia Ciccotelli's Education
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