Alessia Ciccotelli

Alessia Ciccotelli

Physicist, Sordina S.p.A.

Località
Roma, Italia
Settore
Medical Devices

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Alessia Ciccotelli's Overview

Current
  • Physicist LIAC Technical Division at Sordina
Education
Connections

259 connections

Alessia Ciccotelli's Experience

Physicist LIAC Technical Division

Sordina

Società privata non quotata; 51-200 dipendenti; Settore: Medical Devices

luglio 2009Presente (5 anni 3 mesi) Roma, Italia

IORT Dedicated Accelerator Application Specialist
R&D
Linac tuning
Acceptance Test and Training
Commissioning

Alessia Ciccotelli's Patents

  • DEVICE FOR SHAPING AN ELECTRON BEAM OF A MACHINE FOR INTRAOPERATIVE RADIATION THERAPY

    • Europa Modulo brevetto PCT/IT2011/000348
    Inventori: Alessia Ciccotelli, Giuseppe Felici, Vincenzo Iacoboni, Fabio De Angelis, Nicola Mangiaracina, Aquilino Gava

Alessia Ciccotelli's Skills & Expertise

  1. Dosimetry
  2. Technical Documentation
  3. R&D
  4. User Acceptance Testing
  5. Training
  6. Medical Physics
  7. Monte Carlo Simulation
  8. Physics
  9. Scientific Writing

Alessia Ciccotelli's Publications

  • Development and optimization of a beam shaper device for a mobile dedicated IOERT accelerator.

    • Med Phys.
    • ottobre 2012

    The aim of this study was to design and build a prototype beam shaper to be used on a dedicated mobile accelerator that protects organs at risk within the radiation field and conforms the beam to the target geometry during intraoperative electron radiotherapy (IOERT). A dosimetric characterization of the beam shaper device was performed based on Monte Carlo (MC) simulations, as well as experimental data, at different energies, field sizes, and source to skin distances.Methods: A mobile light intraoperative accelerator (LIAC(®), Sordina, Italy) was used. The design of the beam shaper prototype was based on MC simulations (BEAMnrc∕OMEGA and DOSXYZnrc code) for a selection of materials and thicknesses, as well as for dosimetric characterization. Percentage depth dose (PDD) and profile measurements were performed using a p-type silicon diode and a commercial water phantom, while output factors were measured using a PinPoint ion chamber in a PMMA phantom. The output factors (OFs) were determined using different geometrical set-ups and energies.Results: The beam shaper prototype consists of four blades sliding alongside each other and mounted on a special support at the end of the 10 cm diameter PMMA circular applicator. Each blade is made of an upper layer of 2.6 cm of Teflon(®) and a lower layer of 8 mm of stainless steel. All rectangles inscribed in a 5 cm diameter can be achieved in addition to any "squircle-shaped" field. When one side of the rectangular field is held constant and the second side is reduced, both R(50) and R(max) move towards the phantom surface. MC simulation showed an excellent agreement with experimental data (<2%).Conclusions: The beam shaper device is able to provide square∕rectangular∕squircle fields with adequate dose homogeneity for mobile dedicated accelerators, thus allowing conformal treatment with IOERT.

  • Monte Carlo simulation of electron beams generated by a 12 MeV dedicated mobile IORT accelerator.

    • Phys Med Biol.
    • 21 luglio 2011

    The aim of this study was to investigate the dosimetric characteristics of the electron beams generated by the light intraoperative accelerator, Liac® (SORDINA, Italy), using Monte Carlo (MC) calculations. Moreover we investigated the possibility of characterizing the Liac® dosimetry with a minimal set of dosimetric data. In fact accelerator commissioning requires measurements of both percentage depth doses (PDDs) and off-axis profiles for all the possible combinations of energy, applicator diameter and bevelled angle. The Liac® geometry and water phantom were simulated in a typical measurement setup, using the MC code EGSnrc/BEAMnrc. A simulated annealing optimization algorithm was used in order to find the optimal non-monoenergetic spectrum of the initial electron beam that minimizes the differences between calculated and measured PDDs. We have concluded that, for each investigated nominal energy beam, only the PDDs of applicators with diameters of 30, 70 and 100 mm and the PDD without an applicator were needed to find the optimal spectra. Finally, the output factors of the entire set of applicator diameters/bevelled angles were calculated. The differences between calculated and experimental output factors were better than 2%, with the exception of the smallest applicator which gave differences between 3% and 4% for all energies. The code turned out to be useful for checking the experimental data from various Liac® beams and will be the basis for developing a tool based on MC simulation to support the medical physicist in the commissioning phase.

Alessia Ciccotelli's Education

Università di Roma Tor Vergata

Laurea Magistrale, Fisica

20012008

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