Group Manager at the Broad Institute of MIT & Harvard
Greater Boston Area
Group Manager at the Broad Institute of MIT & Harvard
Greater Boston Area
As Manager of the Special Projects Group at the Broad Institute I lead a multidisciplinary team in the development of protocols and processes to facilitate high throughput genome sequencing of challenging samples. Our current projects aim to generate unprecedented amounts of genomic sequence information for Hepatitis C Virus, Dengue Virus, and HIV, using both traditional and new generation sequencing technologies.
Project Management; Operations; Genome sequencing; High-throughput drug screening assay design; A wide array of cell biology techniques.
(Educational Institution; 201-500 employees; Biotechnology industry)
November 2006 — Present (2 years 2 months)
(Educational Institution; 201-500 employees; Biotechnology industry)
July 2005 — November 2006 (1 year 5 months)
This position involved providing technical and scientific support to the Special Projects Group who undertake a variety of custom sequencing and molecular biology projects.
(Non-Profit; 1001-5000 employees; Research industry)
May 2001 — June 2005 (4 years 2 months)
Cecil B. Day Laboratory for Neuromuscular Research
Project 1. To use microarray technology and functional genomics to examine gene expression and possible interacting gene networks in models of muscular dystrophy. This project resulted in the identification of two novel binding partners for our protein of interest.
Project 2. To investigate the role of the muscle protein dysferlin in mediating membrane repair. This project resulted in the discovery of the role of the dysferlin protein in mediating membrane repair.
Project 3. To develop a high-throughput screening (HTS) assay to identify small molecules that modulate the membrane repair response in normal and dystrophic muscle. A preliminary patent application has been filed with the US Patent Office for this novel drug screening assay that has application to the biology of muscle injury and repair including muscular dystrophy and exercise-induced injury.
Management Courses at Harvard Extension 2006 — 2008
- Biotechnology Project Management
- Innovation, Entrepreneurship and Business Transformation
Ph.D., Pharmacology, 1997 — 2001
B.Sc., Pharmacology Major, 1993 — 1997
Teaching: Guest Lecturer at Tufts University Dept of BioMedical Engineering. Guest Speaker at Northeastern University Dept of Pharmaceutical Science. Process Design and Optimization: Six Sigma Black Belt awarded in 2007. Patent Pending on high-throughput assay for drug discovery. Writing: Completed course on 'Creative Non-fiction Writing' at Harvard Extension School. Editor of national quarterly newsletter for BioLink USA-Ireland (2004-2006).
Founding Member, Boston Chapter of BioLink USA-Ireland.