Tulane University School of Medicine
Head of Academic Outreach at Mendeley
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Dr. William Gunn is the Head of Academic Outreach for Mendeley, a research management tool for collaboration and discovery. Dr. Gunn attended Tulane University as a Louisiana Board of Regents Fellow, receiving his Ph.D in Biomedical Science from the Center for Gene Therapy at Tulane University in 2008. His research involved dissecting the molecular mechanism of bone metastasis in multiple myeloma. Frustrated with the inefficiencies of the modern research process, he left academia and established the biology program at Genalyte, a novel diagnostics startup. At Mendeley, he works to make research more impactful and reproducible and is an expert on altmetrics, reproducibility, and open access.
His work at Genalyte, a molecular diagnostics startup, involved developing protein, DNA, and small molecule assays on their novel high-throughput assay platform. He received his PhD from Tulane University, where he studied under Dr. Darwin Prockop at the Tulane Center for Gene Therapy. His dissertation is entitled "Investigating the Role of Human Multipotent Mesenchymal Stromal Cells in the Repair of Bone", in which he developed a model of multiple myeloma in mice and used it to test small molecule inhibitors of the interaction between multiple myeloma and bone precursor cells, promoting bone regeneration and repair of osteolytic lesions. His areas of expertise are bone biology, multiple myeloma, adult stem cells, and disease models.
As Head of Academic Outreach for Mendeley, Dr. Gunn blends deep technical knowledge and industry insight with clear and effective communication skills. He is recognized for his work in the fields of altmetrics and research reproducibility. Dr, Gunn co-directs the Reproducibility Initiative with Elizabeth Iorns and co-organizes Science Online Bay Area with colleagues from other tech companies in the area to bring together people who influence how science is carried out and communicated online.
Designed and managed the Mendeley Advisor program which grew to over a thousand advisors wordwide
Presented at conferences such as Strata, TOCCON, Science Online, Medicine 2.0, Code4Lib
Wrote the Mendeley blog
Developed researcher outreach analytics program
Conducted Mendeley Webinars reaching thousands of attendees
Organized & attended regional events such as Science Hack Day and Open Science Summit
Organized and attended events for the San Diego Biotech community
Covered biotech conferences for the network
This position involves working with the Mendeley team to identify community needs in academic collaboration software and to promote online engagement with their networking service.
This position involves working on a cross-functional team to develop protein, nucleic acid, and small molecule assays for a novel, label-free microfluidics assay platform. I am the lead scientist responsible for development of surface chemistry and assay design.
* Developed protocol for coupling biomolecules to sensor surface
* Performed detailed characterization of dynamic range, sensitivity, and drift
* Interface with engineering team to determine design of assay cartridge
* Optimized surface chemistry to achieve highly-sensitive, zero-drift, low background assay format
* Led team to deliver company development objectives within strict deadlines
* Met with engineering project leads to obtain in-depth familiarity with mechanical, optical, fluidic and software-related aspects of Gen2 and alpha instruments
* Managed inventory of reagents and supplies
* Interviewed candidates for laboratory positions
My Dissertation is entitled "The Role of Human Multipotent Mesenchymal Stromal Cells in the Repair of Bone.”
This work led to the development of a candidate drug for treatment of osteolytic lesions in multiple myeloma.
Adult Stem Cells
* Isolated and cultured multipotent mesenchymal stromal cells (MSCs) from human and rodent sources.
* Designed experiments to identify differentiation and multipotency factors acting on hMSCs.
* Developed novel high-throughput assays for detection and quantitation of osteogenic differentiation.
Multiple Myeloma Animal Model
* Developed animal model for multiple myeloma which reproduced clinically relevant bone involvement.
* Isolated, cultured, and assayed myeloma cell lines, mMSCs, and bone marrow from experimental animals
* Performed necropsy, tissue collection and processing, histological and immunostaining, and ELISA.
The DNA Network is a Feedburner network composed of life science enthusiasts with specialized views in areas such as genetics, biology, biotechnology, health care, and much more.
B.S. Biological Sciences
undergraduate research fellow
My work at Tulane involves self-guided experimental research on the relationship between Human Adult Stem Cells and cancer.
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