Professor at University of Notre Dame
South Bend, Indiana Area
- Current
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- Professor of Chemistry & Biochemistry at University of Notre Dame
- Principal Investigator at Walther Cancer Research Center
- Past
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- Associate Professor at University of Notre Dame
- Assistant Professor at University of Notre Dame
- Postdoctoral Research Associate at Stanford University
- Education
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- Rensselaer Polytechnic Institute
- State University of New York College at Oswego
- Connections
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48
connections
- Industry
- Research
- Websites
Rich Taylor’s Summary
Our group has investigated a number of complex polyketide natural products, with unique or unknown modes of action. Our expertise in the area of synthesis, conformational analysis and polyketide biosynthesis has placed us in a unique position to fully exploit these lead structures potential as therapeutic agents. In the last four years the we have completed the total synthesis of the epothilones A, B, C and D, myriaporones 1, 3 and 4, and most recently, the marine polyketide, peloruside A. In addition, we have prepared modified versions of these compounds, analogues, to learn more about the importance of key structural features with unique perspective focused on the determination of the bound conformation. In addition to our successful total syntheses and medicinal chemistry efforts, our group has already contributed significantly to the field of organic synthesis through the development of a number of new synthetic methodologies that solved key problems in our targeted efforts. In the past several years, we have published new approaches to the synthesis of cyclopropane structural units (ambruticin), hydroxypropionate functionality (myriaporones and tedanolide), trisubstituted olefins (apoptolidin and epothilones) and 1,3-diol monoethers (peloruside A).
Rich Taylor’s Specialties:
organic synthesis, medicinal chemistry and biosynthesis of complex natural products
Rich Taylor’s Experience
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Professor of Chemistry & Biochemistry
University of Notre Dame
(Educational Institution; 1001-5000 employees; Research industry)
August 2004 — Present (4 years)
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Principal Investigator
Walther Cancer Research Center
(Non-Profit; 51-200 employees; Research industry)
July 1999 — Present (9 years 1 month)
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Associate Professor
University of Notre Dame
(Educational Institution; 1001-5000 employees; Higher Education industry)
August 2001 — July 2004 (3 years)
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Assistant Professor
University of Notre Dame
(Educational Institution; 1001-5000 employees; Higher Education industry)
July 1995 — July 2001 (6 years 1 month)
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Postdoctoral Research Associate
Stanford University
(Educational Institution; Research industry)
September 1992 — June 1995 (2 years 10 months)
Developed a total synthesis of the anti-cancer agent taxol
Rich Taylor’s Education
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Rensselaer Polytechnic Institute
Ph.D., Organic Synthesis, 1988 — 1992
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State University of New York College at Oswego
B.S., Chemistry, 1984 — 1987
Additional Information
Rich Taylor’s Websites:
Rich Taylor’s Groups:
American Chemical Society
ACS: Organic Chemistry Division
ACS: Medicinal Chemistry Division
American Society of Pharmacognosy
AAAS
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Obama for America member -
Lifesciences Opportunities in US member -
American Chemical Society member
Rich Taylor’s Honors:
2007 Silveira Distinguished Lecturer; State University of New York at Oswego
2007 Rev. Edmund P. Joyce Award for Excellence in Undergraduate Teaching
2002 Kaneb Teaching Award
2000 Eli Lilly Grantee Award
1998 NSF Early Career Award
Rich Taylor’s Contact Settings
Interested In:
- consulting offers
- new ventures
- expertise requests
- business deals
- reference requests
- getting back in touch
