Reece Hart

Current

Chief Scientist, Genome Commons at UC Berkeley

Past

Scientific Manager, Research Computing & Informatics at Genentech
Scientist at Genentech
Postdoc, Computational Biology Center at IBM T.J. Watson Research Center

Graduate Student at Washington University School of Medicine
Research Assistant at The Salk Institute for Biological Studies
Freelance Programmer at self (Self-employed)

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3 more...

Education

Washington University in St. Louis School of Medicine
Washington University in St. Louis
University of California, San Diego

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Recommended

5 people have recommended Reece

Connections

195 connections

Industry

Biotechnology

Websites

Reece Hart’s Summary

I seek apply my significant and broad expertise in computational biology and data management to investigating significant and unmet questions in human biology. The ideal position will encourage interactions between computational and experimental biologists in a vibrant, collaborative and focused environment.

Reece Hart’s Experience

Chief Scientist, Genome Commons

UC Berkeley

(Educational Institution; Higher Education industry)

September 2009 — Present (3 months)

I am collaborating with UC Berkeley and UCSF faculty to provide data, computing tools, and scientific methods that improve our ability to interpret personal genomic data. See http://genomecommons.org/.
Scientific Manager, Research Computing & Informatics

Genentech

(Privately Held; Biotechnology industry)

August 2005 — September 2009 (4 years 2 months)

I was responsible for developing and implementing the computing strategy that supported Research's scientific mission. My activities included budget, management, capacity planning, project planning, and communication up, down, and across Genentech. I served on Genentech's Technology Council IT steering committee and other enterprise planning groups. [This position overlapped with my scientist role at Genentech.]
Scientist

Genentech

(Privately Held; Biotechnology industry)

June 2001 — January 2008 (6 years 8 months)

I was involved in target discovery in several protein families using advanced sequence- and structure prediction methods. I had joint appointments in the Bioinformatics and Protein Engineering departments. I designed and implemented Unison (http://unison-db.org), a tool for rapid protein mining and sequence analysis that became the backbone of Research's protein annotation infrastructure.
Postdoc, Computational Biology Center

IBM T.J. Watson Research Center

(Public Company; 10,001 or more employees; IBM; Information Technology and Services industry)

January 1999 — May 2001 (2 years 5 months)

I applied pattern discovery techniques to the fully automatic identification of patterns in protein sequences, and showed that these coorespond well with known functional sites (as measured by PROSITE motifs) and in some cases with conserved protein structure.
Graduate Student

Washington University School of Medicine

(Educational Institution; Higher Education industry)

August 1991 — December 1998 (7 years 5 months)

I concurrently pursued graduate programs in Molecular Biophysics and Computer Science.. In 1994, I completed a M.S. thesis with David States in which I implemented a Bayesian peak picking model for ABI automated sequencer data. In 1998, I completed a Ph.D. in Molecular Biophysics with Jay Ponder in which I developed a "smoothable" potential function based on AMBER/OPLSAA, investigated the theoretical connections to simulated annealing, and applied the methodology to small molecule structure predictions and molecular docking predictions.
Research Assistant

The Salk Institute for Biological Studies

(Non-Profit; Biotechnology industry)

June 1988 — June 1990 (2 years 1 month)

Undergraduate research assistant, assisted with mapping several regions of human chromosome 11 and identification of a novel tandem repeat.
Freelance Programmer
self (Self-employed)

(Self-Employed; Myself Only; Computer Software industry)

June 1987 — June 1990 (3 years 1 month)

Freelance computer programming for a local hospital. Initial deployment was during the summer of 1997; subsequent work consisted of updates and improvements over the next 3 years.

Reece Hart’s Education

Washington University in St. Louis School of Medicine

PhD , Molecular Biophysics , 1991 — 1998
Washington University in St. Louis

MS , Computer Science , 1991 — 1994

concurrent with Molecular Biophysics PhD program
University of California, San Diego

BA , Molecular Biology , 1986 — 1990

Additional Information

Reece Hart’s Websites:

Reece Hart’s Interests:

Computational biology / bioinformatics - structure prediction - distant homolog detection - feature-based mining (See http://unison-db.org/) - functional analysis of genomic/somatic variations Computers - Perl - PostgreSQL - Security Other - Private pilot since 1990, instrument rated, >500 hours - Go (http://en.wikipedia.org/wiki/Go_(board_game))