
Director of the Molecular Biology Core Facilities, Principal Research Scientist at Dana-Farber Cancer Institute
Greater Boston Area

Director of the Molecular Biology Core Facilities, Principal Research Scientist at Dana-Farber Cancer Institute
Greater Boston Area
Scientific technology floats my boat. Biotechnology from DNA sequencing, mass spectrometry, to homology algorithms and the incessant increase in efficiency, resolution, and driving down costs coupled to Moore's Law at the waist or making that law look like a tortoise.
The technology of biotechnology down to the minutia is what drives me. Finding a way to squeeze improvements, finding ways to use technology to cut the big corners.
DNA sequencing, Mass spectrometry, peptide synthesis, protein sequencing, Biacore ligand assays currently found in my lab. Thirty years experience in molecular biology, starting with purifying enzymes then finding their activity. I end up writing proposals/grants.
My expertise? Figuring out what is practical, implementing same. Proof of concept is more rewarding. Shift from genomics to proteomics as the mass spectrometry takes over the lab.
Informatics: I know enough not to hurt myself.
(Educational Institution; 1001-5000 employees; Research industry)
March 1980 — Present (28 years 6 months)
Director of the Molecular Biology Core Facilities which includes DNA Sequencing, Genotyping and DNA Synthesis, Protein Sequencing and Peptide Synthesis as well as expanding Mass Spectrometry services. I used to do 100% science but now it seems I am 90% marketing and 5% predicting the biotechnology future. I try and do at least one thing in the lab every day.
At times I advise and consult for other core facilities expanding into my areas of expertise. The science is easy, the cash flow is the difficult part.
Ceramics 2004 — 2005
Botany 2000 — 2000
BS, Botany, 1975 — 1978
Biology 1973 — 1975
DNA Sequencing, Next Generation DNA Sequencing, Single Nucleotide Polymorphisms SNP, Mass Spectrometry, Protein Sequencing, Peptide Synthesis, DNA Synthesis, Amino Acid Analysis, Post-translational modifications PTM and ZFS, pooled zettabyte storage
ABRF; Association of Biomolecular Resource Facilities, member since 1992
NCBI, National Center for Biotechnology Information
ASMS; American Society for Mass Spectrometry, member since 1997
GSA; Genetics Society of America, member since 2007
TPS; The Protein Society, member since 1991
FASEB; Federation of American Societies for Experimental Biology, member since 1991
AAAS; The American Association for the Advancement of Science, member since 1994
BAMBCT; Boston Area Molecular Biology Computer Types, member since 1991
GBMSDG; Greater Boston Mass Spectrometry Discussion Group