Manu Lopus, PhD

Current

• Post-doctoral Scholar at University of California Santa Barbara

Past

• Research Scholar at Indian Institute of Technology Bombay

Education

• Indian Institute of Technology, Bombay
• Mahatma Gandhi University

Recommended

1 person has recommended Manu

Connections

57 connections

Industry

Research

Websites

• My Website

Manu Lopus, PhD’s Summary

Motivated, Biomedical Research Scientist specialized in Cancer Research with a PhD from Indian Institute of Technology Bombay. Three years of post-PhD professional experience with proven capability of independent and original research. Have several publications in high impact scientific journals and encyclopedias. Talent for generating research ideas, and quickly mastering research related technology. Diplomatic and tactful with professionals and nonprofessionals at all levels. Extensive experience in oral and poster presentations including several invited talks in the United States and abroad. Accustomed to multi task. Demonstrated history of timely completion of research projects and grant proposals. Extensive mentoring experience. Flexible and versatile -- able to perform with ease and to maintain a sense of humor under pressure. Poised and competent with ability to transcend cultural differences. Thrive in deadline-driven environments. Competent in team-building skills.

Extensive experience and in-depth understanding in the mechanisms of action of anti-cancer drugs and anti-neurodegenerative agents. I am specialized in screening and development of microtubule-targeted anti-cancer and anti-neurodegenerative drugs.

My focus areas include developing drugs that target and specifically eliminate cancer cells while leaving the normal cells intact. My research group is making good progress in this area with the use of humanized monoclonal antibodies and development of immunoconjugatable drug molecules. In addition, we are working on methods for stabilizing microtubules in nerve cells affacted by neurodegenerative diseases.

Manu Lopus, PhD’s Specialties:

Mechanism and regulation of microtubule dynamics in neurodegenartion and cancer, molecular mechanism of cell division and cell death, mitotic checkpoints.

Manu Lopus, PhD’s Experience

• Post-doctoral Scholar

  University of California Santa Barbara

  (Educational Institution; 5001-10,000 employees; Research industry)

  November 2006 — Present (3 years 2 months)

  Mechanism and regulation of microtubule dynamics in nuerodegeneration and cancer.Evalaution of the effects of anticancer agents and accessory proetins with microtubules.
  
  Experience: Cell culture & cell viability assays, FACS, TEM, confocal micoscopy, spectrophotometer and spectrofluorometer, CD, DIC microscopy.
  
  Softwares: Origin, sigmaplot, RTM, ImagePro, Metamorph, Grafit, MS- word, powerpoint, exel, frontpage, Adobe photoshop.
  
  Publications
  
  1. Manu Lopus, Mythili Yanjerla, and Leslie Wilson (2007) Microtubule Dynamics. Encyclopedia of Chemical Biology. Wiley publications, NJ.
  
  2. Manu Lopus and Dulal Panda (2006). FEBS Journal 273: 2139-2150
  
  3. Ritu Aneja, Manu Lopus et al. (2006) Cancer Research 66, 3782-3791
  
  4. Ritu Aneja, Surya N Vangapandu, Manu Lopus, Dulal Panda, and Harish C. Joshi (2006) Molecular Pharmacology, 69: 1801-1809
  
  5. Ritu Aneja, Surya N Vangapandu, Manu Lopus, et al (2006) Biochemical Pharmacology, doi: 10.1016/j.bcp.2006.05.004

• Research Scholar

  Indian Institute of Technology Bombay

  (Educational Institution; 1001-5000 employees; Higher Education industry)

  July 2001 — September 2006 (5 years 3 months)

  The work sheds light on the molecular, biochemical, and cellular mechanisms of action of two potential anticancer agents, sanguinarine and dolastatin 15.
  
  The effectivenes of these natural products in inhbiting cancer cell proliferation is reported in international journals, and more manucripts are in preparation.

Manu Lopus, PhD’s Education

• Indian Institute of Technology, Bombay

  PhD , Biotechnology , 2001 — 2006

  Activities and Societies:

  Students Gymkhana, IIT Bombay: Served as the Cheif Election Officer, Students General Election (2003)
  
  Research Scholar's Forum: Served as advisor, Cheif Election Officer, Award Committee chairman
  
  General Secretary, School of Biosciences and Bioengineering, IIT Bombay (2003)
  
  Sports Councilor, Hostel-1, IIT Bombay (2002)

• Mahatma Gandhi University

  M.Sc , Life Sciences , 1998 — 2000

  Activities and Societies:

  Black Belt, Shaolin Kung fu, Shaolin Martial Arts Academy, Kerala (2000)
  
  Secretary, Nature Club, St. Berchmans’ College (1999)
  
  Winner, All Kerala Life-Science Quiz Competition (2000)
  
  Campus Correspondent, Career Deepika (A career Magazine), St. Berchmans' College (1997-98)
  
  Volunteer, National Service Scheme, St. Berchmans’ College (1997-2000)
  
  City Coordinator, National Science Olympiad-2001
  
  District Councilor, Indian Institute of Human Rights, Kottayam (2000-2001)

Additional Information

Manu Lopus, PhD’s Websites:

• My Website

Manu Lopus, PhD’s Interests:

Research: Interactions of anti-cancer drugs and accessory proteins with microtubules; mechanism and regulation of microtubule dynamics in neurodegenerative diseases and cancer; control and coordination of cell division. Philosophy: Dialogues bewteen Science and Religion, philosophy of science, Kant, Kuhn, Schopenhauer, Aquinas, and Russel. Martail Arts: Kung Fu ( Ist DAN black belt), Kick boxing, Aikido (5th Kyu, Judo (currantly yellow belt) , and Taekwondo (currently blue belt).

Manu Lopus, PhD’s Groups:

Fellow, Royal Society of Medicine (London)

Member, Royal Microscopical Society (London)

Member, and Councilor of Public Policy, American Society for Cell Biology

Member, National Post doctoral Association, and Councilor of International Post doctoral Council, NPA.

Member, British Association for Advancement of Science

Member, American Association for Cancer Research

Member, New York Academy of Sciences, USA

Member, American Association of Pharmaceutical Scientists, Sigma Xi

•    IIT Alumni
•    Sigma Xi, The Scientific Research Society
•    COPUS - Coalition on the Public Understanding of Science
•    National Postdoctoral Association (NPA)
•    United States Tennis Association
•    The American Society for Cell Biology - ASCB
•    Traditional Kung Fu and Tai Chi Chuan
•    Indian Institute of Technology
•    Martial Arts Black Belt
•    My Own Drum

Manu Lopus, PhD’s Honors:

Biography listed in Marqui's Who's Who in the World (2010)

Biography listed in Marqui's Who's Who in America (2009, 2010)

Fellow, Royal Society of Medicine (Elected 2008)

Best Research Scholar Award, IIT Bombay (2006)

Insitute Citation for Best Organizer, IIT Bombay (2006)

Member of Senate, IIT Bombay (2005 - '06)

Fellowship, National Institute of Health, USA (2006)

Fellowship, Indian Council of Medical Research (2001)

Fellowship, Ministry of Human Resourse Development, Govt. of India (2001)

Member, Sigma Xi (Elected in 2008)

Member, Royal Microscopical Society, UK ( Elected in 2008)

Manu Lopus, PhD’s Contact Settings

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