Patent and Business Development Biotech/Nanotech at
Greater New York City Area
Patent and Business Development Biotech/Nanotech at
Greater New York City Area
Published a legal paper on patent infringement under the doctrine of equivalents: "Application of the Festo Framework in Four Recent Appeal Cases." 89(3) J.Pat.&Trademark Off. Soc'y 216-234 (2007); also translated by the Secretariat of AIPPI-Japan, 52(6): 19 (2007). Writer of a monthly column Nanotechnology and Patents.
Have broad knowledge as well as research experience in areas of cancer (NFkB ), virology (HIV, EIAV) , artheriosclerosis (LDL, CD36), inflammation (IL-1), infectious disease (Leishmania) bacteriology, angiogenesis (VEGF, KSHV-GPCR) and molecular biology techniques, including several scientific publications:
Carvalho M. et. al. (1993) Protein interactions with DNA elements in variant equine infectious anemia virus enhancers and their impact on transcriptional activity. J.Virol., 67:6586-6595.
Carvalho M. and Derse D. (1993) PU.1/Spi-1 proto-oncongene regulates a lentivirus promoter. J.Virol., 67:3885-3890.
Carvalho M. and Derse D. (1993) Physical and functional characterization of transcriptional control elements in the equine infectious anemia virus promoter. J.Virol. 67:2064-2074.
Carvalho M. and Derse D. (1991) Mutational analysis of the equine infectious anemia virus Tat-responsive element. J.Virol. 67:2064-2074.
Copper Deficiency Induced by Tetrathiomolybdate Suppresses Tumor Growth and Angiogenesis. Cancer Res., 17:4854-4859. (2002)
Transcriptional regulation of equine infectious anemia virus. Sem. In Virol. 4:61-68. (1992)
Detecting single base substitutions as heteroduplex polymorphisms. Genomics 12:301-306. (1992).
A minimal lentivirus Tat protein. J. Virol. 65:7012-7015. (1991)
Functional typography of lentivirus Tat proteins defined by domain switching. In: Genetic Structure of HIV, W.A. Haseltine and F. Wong-Staal (eds), Raven Press, New York. (1991)
Tn4527, a Tp Sp/Sm transposon related to Tn7 and flanked by IS1. Plasmid 22:256-259. (1989)
Bar Admissions:
U.S. Patent and Trademark Office.
New York
(Nanotechnology industry)
May 2008 — Present (1 year 7 months)
Focus on nanotechnology. The column discusses US Patent law as applied to nanotech inventions.
(Chemicals industry)
January 2003 — Present (6 years 11 months)
(Educational Institution; 10,001 or more employees; Higher Education industry)
1997 — 2000 (3 years )
Division International Medicine and Infectious Diseases. Conduct research on HIV, IL-1, inflammatory genes, NFkB, transcriptional factors, VEGF, HSHV-GPCR. Supervised thesis research.
(Biotechnology industry)
1995 — 1996 (1 year )
Taught a course (credit) on the basic transcriptional machinary of eucharyotes for both Masters and PhD students in the Dept of Genetics. Supervised thesis research on the screening of HIV strains found in the Brazilian population.
(Biotechnology industry)
1990 — 1993 (3 years )
2003 — 2007
PhD in Genetics , (Virology; molecular biology; transcription) , 1990 — 1993
Research thesis on transcriptional control of a lentivirus (EIAV) related to HIV. Thesis involved the use of molecular techniques such as "gel-shifts," DNAase I footprint, site-specific mutagenesis, CAT assays, Reverse Transcription, DNA sequencing. Author and co-author of several scientific papers (Journal of Virology and others).
Ph.D. , Genetics , 1990 — 1993
Master in Genetics , ( Bacteriology; molecular biology) , 1986 — 1989
Thesis research on bacterial transposons carrying antibiotic resistance genes. Studies on the regulation of a transposon flanked by IS. Co-author of a paper in Plasmid.
Bachelor, Licenciatura , Ciencias Biologicas , 1982 — 1986
Bachelor degree: wrote papers on Zoology, Botanic and Chemistry.
Licenciatura: Certified high school teacher (science). Taught Biology at high school.
Recipient of the Jack Friedman Award given to outstanding medical research conducted by junior faculty members at Weill Cornell University Medical School NY (1998).