
at Infinity Pharmaceuticals
Greater Boston Area

at Infinity Pharmaceuticals
Greater Boston Area
I develop computational approaches to solve biological and chemical problems in drug development. These combine literature searches, sequence analyses, protein structure analyses, biochemical & interaction networks, transcriptional profiling, RNAi technology, protein array technology, and on line databases. I have extensive previous experience with high-throughput annotation of various genomes
Computational biology; protein & DNA sequence analysis; analysis of functional genomics/proteomics data (RNAi, functional protein arrays, transcriptional profiling), extensive understanding of molecular biology/biochemistry/genetics; extensive understanding of drug development
(Public Company; INFI; Pharmaceuticals industry)
May 2009 — Present (7 months)
Application of cancer genomics information to clinical and pre-clinical small molecule oncology therapeutics.
Manage outsourcing relationships with genomics vendors.
(Self-Employed; Myself Only; Biotechnology industry)
November 2006 — Present (3 years 1 month)
Commentary on genomics and proteomics most business days.
(Biotechnology industry)
March 2009 — May 2009 (3 months)
Worked to define knowledge management, informatics strategy & computational platform for 2 small biotech companies. Developed and ran sequence search strategy for target identification. Identified and cross-referenced somatic mutation data to a customer's gene list.
(Privately Held; Biotechnology industry)
January 2007 — March 2009 (2 years 3 months)
Apply data mining and statistical modeling to process improvement problems in synthetic biology & develop new applications for large scale gene synthesis technology. Designing and analyzing complex DNA libraries for protein engineering. Exploring biochemical networks and identifying synthetic biology schemes to create specialty chemicals via fermentation.
(Public Company; 1001-5000 employees; MLNM; Biotechnology industry)
July 2000 — December 2006 (6 years 6 months)
Provides computational and statistical support across the pharmaceutical research & development spectrum. Specific areas of expertise include DNA/protein sequence analysis, interpretation of expression array data, statistical modeling of assays, protein arrays, analysis strategies for genome-wide RNAi data, and interpretation of DNA chip pharmacogenomic results.
(Public Company; 1001-5000 employees; MLNM; Biotechnology industry)
October 1996 — July 2000 (3 years 10 months)
Developed variety of DNA and protein sequence analysis tools to support the discovery of candidates of novel therapeutic protein and small molecule target
(Biotechnology industry)
1993 — 1996 (3 years )
(Biotechnology industry)
1994 — 1995 (1 year )
(Public Company; 1001-5000 employees; Biotechnology industry)
June 1988 — August 1991 (3 years 3 months)
Was intern during summer & winter breaks. Developed & modified software to track documents and in vitro quality results in an FDA regulated environment. Developed equipment inventory system.
PhD , Molecular & Cellular Biology , August 1991 — April 1997
Developed tools to identify genes and transcription factor sites in bacterial genomes. Worked in laboratories of Dr. Walter Gilbert (Nobel laureate) and George Church, two of the pioneers of the human genome project.
B.S. , Biotechnology , August 1987 — August 1991
1984 — 1987
Genomics/proteomics technologies, bioinformatics/computational biology, gardening, history, walking my dog
Editorial Board, Briefings in Bioinformatics (2004-present)
Eagle Scout