LinkedInFedde Groot

Fedde Groot

Anesthesiology resident/specialist trainee at UMC Utrecht

Location
Utrecht Area, Netherlands
Industry
Hospital & Health Care
Previous
  1. The Royal Marsden NHS Foundation Trust,
  2. Northwest London Hospital NHS Trust,
  3. University of Oxford, The Sir William Dunn School Of Pathology
Education
  1. University of Oxford
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256connections
University of Oxford

University of Oxford

Medicine

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Background

Experience

Foundation doctor (FY2)

The Royal Marsden NHS Foundation Trust
(4 months)

Critical Care Unit / Intensive Care

Foundation doctor (FY1)

Northwest London Hospital NHS Trust
(1 year 2 months)Northwick Park Hospital

1. Cardiology
2. Rheumatology & General medicine
3. CoE / Urology

Postdoctoral research fellow

University of Oxford, The Sir William Dunn School Of Pathology
(3 years 1 month)

Transmission of HIV to and from macrophages.

Education

University of Oxford

BM BCh, Medicine

Graduate-entry Medicine, University of Oxford, Magdalen College.

University of Amsterdam

PhD, virology / immunology

Thesis: ‘Dendritic cell-mediated HIV-1 transmission’.

Publications

Architecture and regulation of the HIV-1 assembly and holding compartment in macrophages.(Link)

2011

S Welsch, F Groot, H Kräusslich, OT Keppler and QJ Sattentau: Architecture and regulation of the HIV-1 assembly and holding compartment in macrophages. 2011, Journal of Virology

Authors:

Efficient HIV-1 transmission from macrophages to T cells across transient virological synapses.(Link)

2008

F Groot, S Welsch and QJ Sattentau: Efficient HIV-1 transmission from macrophages to T cells across transient virological synapses. 2008, Blood

Authors:

Dendritic cell-mediated HIV-1 transmission.(Link)

(ISBN: 90-8559-192-9)
2006

PhD Thesis

The carbohydrate at asparagine 386 on HIV-1 gp120 is not essential for protein folding and function but is involved in immune evasion.(Link)

2008

RW Sanders, E van Anken, AA Nabatov, IM Liscaljet, I Bontjer, D Eggink, M Melchers, E Busser, MM Dankers, F Groot, I Braakman, B Berkhout and WA Paxton: The carbohydrate at asparagine 386 on HIV-1 gp120 is not essential for protein folding and function but is involved in immune evasion. 2008, Retrovirology

Authors:

Sialoadhesin (CD169) expression in CD14+ cells is upregulated early after HIV-1 infection and increases during disease progression.(Link)

AC van der Kuyl, R van den Burg, F Zorgdrager, F Groot, B Berkhout and M Cornelissen: Sialoadhesin (CD169) expression in CD14+ cells is upregulated early after HIV-1 infection and increases during disease progression. 2007, PLoS ONE

Authors:

Opposing roles of blood myeloid and plasmacytoid dendritic cells in HIV-1 infection of T cells: transmission facilitation versus replication inhibition.(Link)

2006

F Groot, TM van Capel, ML Kapsenberg, B Berkhout and EC de Jong: Opposing roles of blood myeloid and plasmacytoid dendritic cells in HIV-1 infection of T cells: transmission facilitation versus replication inhibition. 2006, Blood

Authors:

Dendritic cell-mediated HIV-1 transmission to T cells of LAD-1 patients is impaired due to the defect in LFA-1.(Link)

2006

F Groot, TW Kuijpers, B Berkhout and EC de Jong: Dendritic cell-mediated HIV-1 transmission to T cells of LAD-1 patients is impaired due to the defect in LFA-1. 2006, Retrovirology

Authors:

Differential susceptibility of naïve, central memory and effector memory T cells to dendritic cell-mediated HIV-1 transmission.(Link)

2006

F Groot, TMM van Capel, JHN Schuitemaker, B Berkhout and EC de Jong: Differential susceptibility of naïve, central memory and effector memory T cells to dendritic cell-mediated HIV-1 transmission. 2006, Retrovirology

Authors:

Histatin 5-derived peptide with improved fungicidal properties enhances HIV-1 replication by promoting viral entry.(Link)

2006

F Groot, RW Sanders, O ter Brake, K Nazmi, ECI Veerman, JGM Bolscher and B Berkhout: Histatin 5-derived peptide with improved fungicidal properties enhances HIV-1 replication by promoting viral entry. 2006, Journal of Virology

Authors:

Stimulated plasmacytoid dendritic cells impair human T cell development.(Link)

2006

H Schmidlin, W Dontje, F Groot, SJ Ligthart, AD Colantonio, MECM Oud, EJM Schilder-Tol, M Spaargaren, H Spits, CH Uittenbogaart and B Blom: Stimulated plasmacytoid dendritic cells impair human T cell development. 2006, Blood

Authors:

Lewis X component in human milk binds DC-SIGN and inhibits HIV-1 transfer to CD4+ T-lymphocytes.(Link)

2005

MA Naarding, IS Ludwig, F Groot, B Berkhout, TBH Geijtenbeek, G Pollakis and WA Paxton: Lewis X component in human milk binds DC-SIGN and inhibits HIV-1 transfer to CD4+ T-lymphocytes. 2005, Journal of Clinical Investigation

Authors:

Lactoferrin prevents dendritic cell-mediated HIV-1 transmission by blocking the DC- SIGN—gp120 interaction.(Link)

2005

F Groot, TBH Geijtenbeek, RW Sanders, CE Baldwin, M Sanchez-Hernandez, R Floris, Y van Kooyk, EC de Jong and B Berkhout: Lactoferrin prevents dendritic cell-mediated HIV-1 transmission by blocking the DC- SIGN—gp120 interaction. 2005, Journal of Virology

Authors:

Initiation of HIV-1 reverse transcription is regulated by a primer activation signal.(Link)

2001

N Beerens, F Groot, and B Berkhout: Initiation of HIV-1 reverse transcription is regulated by a primer activation signal. 2001, Journal of Biological Chemistry

Authors:

Stabilization of the U5-leader stem in the HIV-1 RNA genome affects initiation and elongation of reverse transcription.(Link)

2000

N Beerens, F Groot, and B Berkhout: Stabilization of the U5-leader stem in the HIV-1 RNA genome affects initiation and elongation of reverse transcription. 2000, Nucleic Acids Research

Authors:

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