Research & Development Scientist at Draths Corporation
Lansing, Michigan Area
Research & Development Scientist at Draths Corporation
Lansing, Michigan Area
● I worked out a multi-step chemical process, based on which a pilot plant is now being built.
● Highly motivated, team-oriented, and goal-driven scientist with 8 years of chemistry research and development expertise.
● Creative and analytical problem solver who thrives on new challenges in a fast-paced environment.
● Accomplished the total synthesis of a marine natural product.
● Isolated novel, low-abundant, marine natural products (0.0001 mass % each).
● Extensive hands-on experience and profound knowledge of all classic and modern organic synthesis methods and modern analytical instrumentation.
● Extensive knowledge of the chemical literature. Fluent in English. Native speaker of German. Reading knowledge of Russian.
● Motivated speaker, and excellent communication (oral and written) skills.
● Team Leader
● Organic Synthesis
● Medicinal Chemistry
● Process Chemistry
● Renewable Resources
● Protein Crystallography
● Genomics: Genetic Genealogy & 23andMe/deCODEme for medical information [SNP-disease association studies]
(Renewables & Environment industry)
August 2008 — Present (1 year 4 months)
● Development of efficient chemical transformations to convert fermentation products, which are produced from renewable resources (glucose) as the nutrient, into high-value chemical intermediates that are currently being synthesized from oil.
● Skills and experience developing chemistry of highly oxygenated secondary metabolites.
● Development of novel catalytic processes.
● Based on a multi-step process I worked out, a pilot plant is now being built.
● Experience working in the dynamic environment of a start-up company.
● Supervise technicians.
(Pharmaceuticals industry)
March 2007 — Present (2 years 9 months)
● Professional scientific consultation service.
● Translation service from German to English.
(Educational Institution; 1001-5000 employees; Higher Education industry)
October 2002 — July 2008 (5 years 10 months)
● Completed the total synthesis of the marine natural product iejimalide B.
● Developed improved synthetic routes to target structures.
● Applied the Shiina macrolactonization to the formation of a 24-membered macrolactone, which is the largest ring closed by a Shiina macrolactonization reported to date.
● Established an efficient Pt-catalyzed hydroboration of complex molecules.
● Synthesized iejimalide derivatives to establish structure-activity relationship (SAR).
● Synthesized an iejimalide-fluorophore conjugate which allowed cellular localization study.
● Isolated highly anti-tumor active marine natural products by flash chromatography and HPLC from a crude tunicate acetone extract.
● Trained, guided, and supervised undergraduate research students.
● Took responsibility for maintaining lab equipment and training new graduate students.
● Presented results at meetings and wrote papers.
(Educational Institution; 10,001 or more employees; Higher Education industry)
July 2001 — September 2002 (1 year 3 months)
● Synthesized alkylated and phosphorylated nucleosides for use in NMR studies.
● Synthesized linked fluorophore-amine molecules.
● Developed new synthetic routes to target structures.
● Managed database of compounds that were submitted for biological testing.
● Trained, guided, and supervised undergraduate research students.
● Took responsibility for maintaining lab equipment and training new graduate students.
(Pharmaceuticals industry)
October 1995 — August 1996 (11 months)
● Crystallized thermolysin mutants.
● Solved and refined protein crystal structures and collected data at a synchrotron.
(Research industry)
November 1993 — June 1994 (8 months)
● Synthesized and characterized macrocyclic compounds and their metal complexes.
(Pharmaceuticals industry)
September 1993 — October 1993 (2 months)
● Isolated and purified natural products using HPLC.
Ph.D. , Chemistry , 1996 — 2001
● Synthesized model compounds of the active site of the metalloenzyme nitrile hydratase to study its enzymatic mechanism. These were Fe and Co complexes in a mixed nitrogen/sulfur coordination sphere.
● Designed new ligands and developed new synthetic routes to target structures.
● Presented results at meetings and wrote papers.
● Took responsibility for maintaining lab equipment and training new graduate students.
● Trained, guided, and supervised undergraduate research students.
● Taught organic and introductory classes and laboratories.
Research for Diplom-Chemiker (German M.S. in Chemistry) , Organic Chemistry , 1994 — 1995
● Designed and synthesized novel pyrroles, oligopyrroles, and expanded porphyrins.
Diplom-Chemiker (German M.S. in Chemistry) , Chemistry , 1990 — 1995
Chemistry, Science in General, Reading, Running, Traveling, Archaeology, Genetic Genealogy
Member, American Chemical Society (ACS)
Member, German Chemical Society (Gesellschaft Deutscher Chemiker, GDCh)
Member, International Society of Genetic Genealogy (ISOGG)