Bioinformatics Scholar at Duke University Medical Center
Raleigh-Durham, North Carolina Area
- Current
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- Duke Bioinformatics Scholar at Duke University Medical Center
- Past
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- Director, Duke Bioinformatics Group at Duke University
- Director, Duke Bioinformatics Group at Duke Institute for Genome Sciences & Policy
- Director, Bioinformatics at Duke University (IGSP)
- Director, Bioinformatics at RTI International
- Director, Bioinformatics at Hospital for Sick Children
- Associate Professor, Medical Biophysics at The University of Toronto
- Consulting VP of Genomic Information at Ceres Biotech
- Director, Bioinformatics and Genomics at ChemGenics Pharmaceuticals
- Director, Computational Biology at The MITRE Corporation
- Assistant Professor at The Johns Hopkins University School of Medicine
- Education
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- The University of Georgia
- University of Maryland Baltimore County
- North Carolina Central University School of Law
- Connections
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66
connections
- Industry
- Biotechnology
- Websites
A. Jamie Cuticchia’s Summary
Dr. A. Jamie Cuticchia, the Director of the Duke Bioinformatics Group (DBIG), has over 20 years’ academic and industry experience leading groups in computational biology, genomics, high-performance computing, software engineering, and genome database construction. He has held numerous leadership positions including professorships at the Johns Hopkins University School of Medicine and the University of Toronto Faculty of Medicine. Dr. Cuticchia founded the Ontario Center for Genomic Computing, a Top 500 Supercomputing Center and the largest supercomputing center devoted solely to addressing issues of life sciences. He also held several full and part-time industrial positions including Director of Computational Biology for the MITRE Corporation, Director of Bioinformatics and Genomics for ChemGenics Pharmaceuticals, Director of Drug Discovery Information Technology for Millennium Pharmaceuticals, Consulting Vice President of Genomic Information for Ceres Genomics, and CIO for SynX Pharmaceuticals, and scientific founder of New Chemical Entities. Immediately prior to coming to Duke, he was Director of Bioinformatics for the Research Triangle Institute. Dr. Cuticchia was ranked in 2001 as a Genome Technology All-Star, one of the Top 3 Bioinformaticians worldwide responsible for the success of the Human Genome Project. He has numerous publications including four books on the human genome.
A. Jamie Cuticchia’s Specialties:
Genetics, Genomics, Bioinformatics, Computational Biology, Clinomics, Clinical Trials, Drug Discovery, Scientific Publishing
A. Jamie Cuticchia’s Experience
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Duke Bioinformatics Scholar
Duke University Medical Center
(Educational Institution; Hospital & Health Care industry)
January 2009 — Present (7 months)
Newly created position for coordinating bioinformatics research both internally and setting a national strategy for bioinformatics, especially in the area of Cancer Research.
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Director, Duke Bioinformatics Group
Duke University
(Educational Institution; Higher Education industry)
February 2006 — January 2009 (3 years)
The Duke Bioinformatics Group was established to create an organization which would synergize bioinformatics core services and collaborative research across both the Duke Institute for Genome Sciences & Policy and the Duke Comprehensive Cancer Center. Responsibilities include providing bioinformatics infrastructure to support research in –omics, such as the microarray analysis, and the integration of clinical and –omics data for research in genomic medicine.
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Director, Duke Bioinformatics Group
Duke Institute for Genome Sciences & Policy
(Biotechnology industry)
2006 — January 2009 (3 years)
See previous position.
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Director, Bioinformatics
Duke University (IGSP)
(Educational Institution; Higher Education industry)
February 2006 — January 2009 (3 years)
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Director, Bioinformatics
RTI International
(Non-Profit; 1001-5000 employees; Research industry)
March 2001 — February 2006 (5 years)
Responsibilities included the marketing and acquisition of business in genomics and bioinformatics for RTI. Developed strategic and tactical plans for increasing RTI’s business and capabilities; identify research business opportunities in government and private industry; market RTI’s capabilities to potential clients; lead research projects and work on projects that are led by others; make presentations and prepare papers that enhance RTI’s reputation in bioinformatics; identify and recruit additional staff necessary to grow the program; and mentor staff.
• Served a project director, principal investigator, or co-PI on $35,000,000 of genomic or epidemiologic research.
• Established a high-performance computational center for biological research.
• Directed the GDB Human Genome Database in its transition to RTI.
• Built a group of diverse scientific expertise including computer science, modeling, bioinformatics analysis, human genetics, and plant genomics. -
Director, Bioinformatics
Hospital for Sick Children
(Government Agency; 1001-5000 employees; Hospital & Health Care industry)
August 1997 — November 2001 (4 years 4 months)
Major Projects/Achievements
- Raised over $50,000,000 in funds to support bioinformatics through government and private organizations, setting a record for the amount of money brought in by a single investigator at the Hospital for Sick Children.
- Developed a core-facility providing bioinformatics services to over 300 researchers.
- Supervised a group of 25 individuals with PhDs, MDs, MSs, and BAs with advanced training in computer science, engineering, mathematics, and physics.
- Re-established the GDB Human Genome Database, noted by HUGO (The Human Genome Organization) as the most noteworthy genomic event in 1999.
- Collaborated with several companies to provide bioinformatics services through HSC.
- Played a role in the design and creation of clinical trials databases. -
Associate Professor, Medical Biophysics
The University of Toronto
(Educational Institution; 5001-10,000 employees; Research industry)
January 1998 — March 2001 (3 years 3 months)
Related Roles:
Hospital for Sick Children:
Head of Bioinformatics. Led the development of Bioinformatics/Computational Biology. Developed both a core facility for serving the 1,500+ research scientists while working with senior hospital officials to set academic priorities for future recruitments.
Co-Director of The Centre for Applied Genomics:
Provided the bioinformatics infrastructure, support, and direction for the genome centre.
Managing Director of the GDB Human Genome Database:
Established the move from the US of the second most used database for human genomic information.
Founder and Director of the Ontario Centre for Genomic Computing:
Created the largest publicly accessible Application Service Provider (ASP) for bioinformatics in the world, consistently ranked in the worldwide Top500 list of supercomputers. -
Consulting VP of Genomic Information
Ceres Biotech
(Biotechnology industry)
1999 — 2000 (1 year)
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Director, Bioinformatics and Genomics
ChemGenics Pharmaceuticals
(Privately Held; 51-200 employees; Biotechnology industry)
February 1996 — August 1997 (1 year 7 months)
Responsible for leading the bioinformatics and genomics departments of a 100 person biotechnology company. Budgetary responsibility of approximately one-third of the research and development expenditure through a matrix management system.
Major Projects/Achievements:
- Developed the “Drug Source” project which organized the 1,000,000+ natural products available for drug screening.
- Developed a high-throughout LIMS system that was used to manage the automated screening procedure and interfaced with robotics and other screening technology.
- Co-developed with Pfizer a system for prioritization of drug targets for further genomic analysis using a proprietary bioinformatics system.
- Established a core group and core technologies for bioinformatics analysis for the company.
- Played a key role in merging the bioinformatics technologies of ChemGenics with Millennium Pharmaceuticals. -
Director, Computational Biology
The MITRE Corporation
(Non-Profit; 1001-5000 employees; Research industry)
November 1995 — February 1996 (4 months)
Responsible for leading the use of recently unclassified US Department of Defense technology into the biotechnology and pharmaceutical sectors.
Major Projects/Achievements:
- Built from scratch a team of individuals to employ the “think-tank” technologies of MITRE to the biotechnology and pharmaceutical sectors.
- Successfully negotiated and lead the first projects in this area. Unfortunately, confidentiality prevents discussion regarding the customers and the work products.
- Developed technology used in Genome Explorer for integrating biological data across multiple databases. This technology was a precursor to many of the technologies used for tools such as IBM Discoverylink or NetGenics.
- Taught courses in genetics, molecular biology, and bioinformatics to MITRE staff.
- Responsible for interacting with scientists at major pharmaceutical companies as part of the MITRETEK (the commercial spin-off of MITRE) marketing plan. -
Assistant Professor
The Johns Hopkins University School of Medicine
(Educational Institution; 1001-5000 employees; Higher Education industry)
March 1992 — November 1995 (3 years 9 months)
Responsible for coordinating the needs of human genome project researchers with informatics support available from the GDB Human Genome Data Base Project. Part of the Senior Management Team for the largest bioinformatics project devoted to the human genome program.
Major Projects/Achievements:
- Published four books from 1992-1996 that outlined the state of the human gene map during the period of the human genome project when most disease genes were isolated.
- Founding faculty member of the Division of Biomedical Information Sciences and developer of course on the role of computation in the human genome project.
- Provided the strategic leadership for data collection procedures and interfacing with all major genome centers.
- Budgetary oversight ($2,000,000 per year) of all data activities of project, and NIH Principal Investigator for that core.
- Coordination of two satellite curation centers (Winnipeg and Dallas).
A. Jamie Cuticchia’s Education
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The University of Georgia
PhD , Genetics , 1987 — 1992
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University of Maryland Baltimore County
BA , Biological Sciences , 1984 — 1987
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North Carolina Central University School of Law
Additional Information
A. Jamie Cuticchia’s Websites:
A. Jamie Cuticchia’s Groups:
Human Genome Organisation (HUGO), Human Genome Variation Society (HGVS), Duke University
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Ceres Alumni -
Biorepository Hub
A. Jamie Cuticchia’s Honors:
National Cancer Institute, caBIG Award of Excellence
Research Triangle Institute President’s Award
Inductee, Genome Academy
Genome Technology All-Star
Recipient of SGI Endowment in Bioinformatics
SGI Showcased Outstanding Researcher
Canadian Top 40 under 40 Nominee
Recipient of IBM SUR Award for Bioinformatics
Elected to Sigma Xi Honor Society
University of Georgia Travel Award
Genetics Department-NIH Training Award
University of Georgia Fellow
Genetics Society of America Travel Award
Outstanding Graduate in the Biological Sciences
Honors Program Graduate in addition to Cum Laude
American Legion Oratorical Scholarship
University of Maryland Baltimore County Distinguished Scholar
Maryland Distinguished Scholar (highest award in State academics)
A. Jamie Cuticchia’s Contact Settings
Interested In:
- career opportunities
- consulting offers
- new ventures
- job inquiries
- expertise requests
- reference requests
- getting back in touch
