
Contractor at AstraZeneca
Göteborg Area, Sweden

Contractor at AstraZeneca
Göteborg Area, Sweden
• A very experienced and accomplished multidisciplinary senior scientist with team leadership, project leadership and managerial successes.
• Record of high achievement in bioinformatics, cheminformatics, proteomics, genomics, drug target characterisation, protein chemistry and chromatography
• Broad background in pharmaceutical and biotechnology R&D
• 77 publications, 45 in PubMed, 22 published patents
• 25 Invited external presentations in the last five years
• Wide network of academic and commercial contacts
• Currently interested in new positions and consultancy work
• Futher details at http://www.cdsouthan.info/CDS_prof.htm
Protein and nucleotide databases, drug targets, proteases, pathways, systems biology, omics data, patent investigations, running surveys, cheminformatics of sequence-target-activity in PubChem and GVKBIO databases, protein structure-ligands, comparative genomics, variation for disease-association or pharmacogenomics, web-based bioinformatics resources, documentation for databases and software, mass-spectrometry proteomics, protein separation, 2D gels, HPLC, student supervision
(Pharmaceuticals industry)
July 2009 — Present (5 months)
(Public Company; AZN; Pharmaceuticals industry)
July 2009 — Present (5 months)
Working on the Knowledge Engineering project
(Educational Institution; Primary/Secondary Education industry)
2004 — Present (5 years )
(Pharmaceuticals industry)
May 2008 — July 2009 (1 year 3 months)
Integrated own and other expert inputs to develop a comprehensive questionnaire that has captured key metrics, operational and content information from database providers for the European Life sciences Infrastructure for Biological Information (ELIXIR) project (http://www.elixir-europe.org/)
Checked URLs, compiled status listing and mailed survey to over 500 databases in Europe
Survey results used for ELIXIR presentations by myself, the EBI Director, Assistant Director and other Work Package leaders
Committee member for Work Package 2, ELIXIR Strategy for Data Resources
Extensive report compiled for ELIXIR documentation
Inputs to EBI Druggablity Portal and Biomolecular Interaction Standards specification
(Pharmaceuticals industry)
December 2007 — May 2008 (6 months)
see http://www.cdsouthan.info/Consult/CDS_cons.htm
(Public Company; 10,001 or more employees; Pharmaceuticals industry)
March 2004 — November 2007 (3 years 9 months)
Wrote user manual for major global database of targets, compounds and assay data with 300+ users
Internal champion for awarenes and exploitation of PubChem synergies with internal bioactive compound sources.
Gave bioinformatic support for 20 target and compchem projects.
Provided expert consultation on gene>pharmacology mappings.
Fostered contacts for knowledge extraction for target>compound including managers at GVKBIO, PubChem, and DrugBank.
Managed team of five Bioinformaticians and two Masters Students.
Awarded promotion and Swedish expert tax exemption.
Served on global Bioinformatics Strategy Steering Group and Target Development & Bioinformatics Section Management Team.
Lead Working Group on external bioinformatics resources.
Contributed to business case for workflow investment
Appointed Special Professor in Proteomics at University of Nottingham
Seven publications and ten external presentations.
(Public Company; 51-200 employees; Biotechnology industry)
2002 — 2004 (2 years )
Mining unknown proteins, splice variants, SNPs and other marketing examples from the Human Protein Atlas database.
Project on gene number presented to Confirmant Scientific Advisory Board resulted in major revenue gain for OGS
Inputs for database rationalisation, cross-species comparisons, and analysis of unknown proteins provided for major OGS customer projects
Delivered 11 external presentations, four papers, three book chapters.
Two Bioinformatics M.Sc. students awarded distinctions.
(Public Company; 51-200 employees; Biotechnology industry)
2001 — 2002 (1 year )
(Public Company; Pharmaceuticals industry)
1987 — 2000 (13 years )
(Non-Profit; 501-1000 employees; Research industry)
January 1985 — October 1987 (2 years 10 months)
(Educational Institution; 501-1000 employees; Research industry)
1984 — 1985 (1 year )
(Government Agency; 501-1000 employees; Research industry)
1979 — 1983 (4 years )
(Government Agency; 501-1000 employees; Research industry)
1977 — 1979 (2 years )
Ph.D. (Rer.nat) , Thesis "Investigations on Genetic Variants of Fibrinogen" , 2000 — 2003
M.Sc. , Virology, Thesis: "Strutural Studies on the Granulosis Virus of the Indian Meal Moth" , 1974 — 1975
B.Sc. Hons , Biochemistry , 1970 — 1974
International Society for Computational Biology, Biochemical Society (UK), Royal Society of Chemistry Protein and Peptide Sceince Group, European Bioinformatics Institute Industry Program, Association of Biomolecular Resource Facilities