
Research Associate at Cephalon (biotech)
Greater Philadelphia Area

Research Associate at Cephalon (biotech)
Greater Philadelphia Area
I am a creative Scientist with 27 years in preclinical pharmaceutical research, and 15 years of experience in Information Technology.
Starting from target identification, I conduct literature searches, produce and modify experimental procedures, validate with reference compounds, screen in-house novel compounds, collect and analyze data, and write reports.
I have been rated by my supervisors as exceptional in creativity, innovation, teamwork, judgment, and analytical skill.
• IN-VIVO studies: Pharmaceutical research in cognition and pain/inflammation, as well as in the cardiovascular and gastrointestinal fields of study. Performed aseptic survival surgery on rats.
• IN-VITRO studies: Experience with a large number of unique tissue preparations obtained from diverse species.
(Public Company; CEPH; Pharmaceuticals industry)
April 2004 — Present (5 years 8 months)
I am part of the Neurobiology group, involved in the discovery of novel antinociceptive agents. I utilized Hargreaves apparatus and von Frey filiaments to study pain and inflammation.
Prior to this effort, I characterized novel H3 antagonists using a rat dipsogenia model and the Social Recognition behavioral model, leading to the nomination of a novel H3 antagonist to preclinical development.
(Pharmaceuticals industry)
2004 — Present (5 years )
(Research industry)
November 2003 — January 2004 (3 months)
I administered the nation's largest database of Type I Diabetes families [503 families, over 6500 individuals]. Ran queries against data to answer researcher's questions, created reports, produced targeted mailing lists, entered and error-checked data. Worked on Pennsylvania Grant to study Diabetic Retinopathy; examined Ophthalmologist medical records to divide subjects into groups based on rate of progression of disease state.
(Public Company; 5001-10,000 employees; Pharmaceuticals industry)
August 2002 — February 2003 (7 months)
Implanted arterial catheters into rat femoral artery. Developed and ran 4x4 and 6x2 Latin Square studies. Determined post-treatment Ca++ plasma levels. Centrifuged and collected plasma for PTH and Drug Level analysis. Analyzed data.
(Public Company; MRK; Pharmaceuticals industry)
1980 — February 2001 (21 years )
Working in Neuropharmacology, Cardiovascular, and Gastroenterology, I gathered information on target medical conditions, then modified existing techniques and created new ones to suit the current research focus. I wrote protocols and tested the company's novel compounds for effectiveness in treating human disease. After experimentation concluded, I gathered the data, performed statistical analysis, and created charts visually representing the analyzed data.
Corporate-wide Information Technology Access: I applied my Information Technology skills and knowledge to increase productivity across all Merck divisions on several projects:
* Chaired the Pharmacology department Y2K committee
* Created corporate Policies and Guidelines for Intranet websites and organizations;
* Developed websites on Merck's corporate Intranet; consolidated 35 worldwide groups.
* Served on Merck Webmaster's Core Team, which was charged with strategic redesign of the Merck Intranet.
National Education Development Test; 91st percentile