to BBB is a clinical stage biotechnology company focusing on enhanced drug delivery across the blood-brain barrier. The Company is developing novel treatments for devastating brain disorders, such as brain cancer, neurodegenerative diseases and lysosomal storage diseases, by combining existing drugs with the G Technology®, to BBB’s proprietary brain delivery platform. This technology combines the widely used drug delivery approach of pegylated liposomes with the endogenous tripeptide glutathione as targeting ligand in a novel and safe way. Together with several top tier pharma and biotech companies, to BBB is investigating the versatility of the G Technology® for drugs that are unable to reach the brain within a tolerable therapeutic window. to BBB is applying the G Technology® for the delivery of doxorubicin for the treatment of brain cancer as its internal lead product 2B3 101.
to-BBB is headquartered in the Netherlands at the Leiden Bio Science Park and established a fully owned subsidiary, to-BBB Taiwan Ltd., in Taipei, Taiwan. Investors in to-BBB include Aescap Venture, Antea Participaties, Jonghoud International, the Industrial Bank of Taiwan Management Corporation (IBTM) and a consortium of informal investors.
Specialties
drug delivery, blood-brain barrier, brain cancer, neuroinflammation
to-BBB Activity on LinkedIn
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to-BBB has a new Business Intern
Eline Wortman is now Business Intern
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to-BBB Mobile phone collection @hersenstichting : box now also @PharmingGroup , among 15 other locations; score so far: more than €500 collected! -
to-BBB Mobile phone collection @hersenstichting : boxes now also at BioPartner Accelerator and Incubator buildings, and Hogeschool @HSLeiden ! -
to-BBB The Dutch brain drug delivery company is looking for Research Technician CNS Targeting! Job profile: http://www.tobbb.com/company/Careers -
to-BBB Mobile phone collection @hersenstichting : many thanks for #JCIHaaglanden @Cva_2012 for their donations to our charity on an excellent event -
to-BBB to-BBB and lead product 2B3-101 on Brain Cancer featured in newsletter of the International Brain Tumour Alliance, a brain tumor patient advocacy group: http://t.co/hvg1jqYR -
to-BBB Mobile phone collection @hersenstichting : boxes now @AxonLawyers , @BaseClear , @GenzymeNL , @UniLeiden , @LeidenScience , and 8 other companies!