to BBB is a clinical stage biotechnology company focusing on enhanced drug delivery across the blood-brain barrier. The Company is developing novel treatments for devastating brain disorders, such as brain cancer, neurodegenerative diseases and lysosomal storage diseases, by combining existing drugs with the G Technology®, to BBB’s proprietary brain delivery platform. This technology combines the widely used drug delivery approach of pegylated liposomes with the endogenous tripeptide glutathione as targeting ligand in a novel and safe way. Together with several top tier pharma and biotech companies, to BBB is investigating the versatility of the G Technology® for drugs that are unable to reach the brain within a tolerable therapeutic window. to BBB is applying the G Technology® for the delivery of doxorubicin for the treatment of brain cancer as its internal lead product 2B3 101.
to-BBB is headquartered in the Netherlands at the Leiden Bio Science Park and established a fully owned subsidiary, to-BBB Taiwan Ltd., in Taipei, Taiwan. Investors in to-BBB include Aescap Venture, Antea Participaties, Jonghoud International, the Industrial Bank of Taiwan Management Corporation (IBTM) and a consortium of informal investors.
Specialties
drug delivery, blood-brain barrier, brain cancer, neuroinflammation
New hires at to-BBB
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Scientist CNS Targeting
Came from...
VU University Amsterdam, Post-Doctoral fellow
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Scientist CNS targeting
Came from...
Leiden University Medical Center, Post-doctoral Research Fellow
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Business Trainee
Came from...
Department of Human Nutrition, Wageningen University, Student assistant
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