Smith & Nephew plc develops and manufactures various medical devices. The company offers reconstruction implants that include hip, knee, and shoulder joints; and ancillary products, such as bone cement and mixing systems used in the cemented reconstruction joint surgery. It also offers trauma products, which comprise internal and external fixation devices, and orthobiological materials used in the stabilization of fractures and deformity correction procedures; and clinical therapies, which comprise products applied in clinic setting and bone growth stimulation, and joint fluid therapy. In addition, Smith & Nephew provides endoscopic techniques, educational programs, and value-added services for surgeons to treat and repair soft tissue, articulating joints, and vascular structures. It offers surgeons endoscopic technologies for surgery, including specialized devices, fixation systems, and bioabsorbable materials to repair damaged tissue; fluid management and insufflation equipment for surgical access; digital cameras, digital image capture, central control, multimedia broadcasting, light sources, and monitors to assist with visualization; and radiofrequency wands, electromechanical and mechanical blades, and hand instruments for resecting damaged tissue. Further, Smith & Nephew offers initial wound bed preparation and wound closure products targeted at chronic wounds. The company sells its products to medical and surgical service providers worldwide. It has a strategic alliance with Q-MED AB to develop and commercialize Q-MED’s proprietary technology for the production of stabilized non-animal hyaluronic acid for the management of orthopaedic conditions and diseases. Smith & Nephew also has a research collaboration with MIV Therapeutics, Inc. to develop coatings and drug delivery systems for orthopedic devices. The company was founded in 1856 and is headquartered in London, the United Kingdom.