Ligand Pharmaceuticals Incorporated, a biotech company, engages in the discovery and development of drugs in the United States. It has research and development collaborations with pharmaceutical companies, including GlaxoSmithKline; Wyeth; Pfizer, Inc.; and TAP Pharmaceutical Products, Inc. for the treatment of market indications, such as thrombocytopenia, osteoporosis, menopausal symptoms, and frailty. The company’s partnered products include Eltrombopag, a small-molecule TPO mimetic for thrombocytopenia, which is in phase III clinical trials; bazedoxifene, a monotherapy for osteoporosis; Aprela, a combination of bazedoxifene with PREMARIN for osteoporosis prevention, and vasomotor symptoms of menopause; and lasofoxifene, for osteoporosis and vaginal atrophy, which is in phase III clinical trials. Ligand Pharmaceuticals Incorporated was founded in 1987 and is headquartered in San Diego, California.