The mission of CUMC’s Clinical and Translational Science Award (CTSA) is to transform the culture of research to accelerate the discovery and implementation of new treatments and prevention strategies. CUMC is accomplishing this goal by establishing the Irving Institute for Clinical and Translational Research, which is the academic home for patient oriented research. The Irving Institute faculty include some of CUMC’s most senior researchers, who provide leadership and mentoring to junior faculty, fellows, and trainees. Specially-appointed junior faculty, the "Irving Fellows," work with senior faculty to develop novel approaches to advancing multi- and interdisciplinary clinical and translational research. The 10 key resources of the Irving Institute include support in biomedical informatics, study design and biostatistics, bioethics, regulatory issues, and core laboratory facilities, among others.