Applied Imaging Corp. engages in the development, manufacture, and marketing of automated genetic imaging systems for use in cytogenetic laboratories. It supplies automated image capture and analysis systems for the detection and characterization of chromosomes and molecular markers in genetics and cancer applications. The company provides CytoVision, PowerGene, and QUIPS systems to analyze human chromosome preparations using software classification algorithms and a user interface. These systems also incorporate the capability to analyze and record images produced by genetic research assays that employ fluorescent in situ hybridization (FISH), a technique to detect chromosomal changes in cells using fluorescent-tagged DNA segments or comparative genomic hybridization techniques to measure the amount of a genetic sequence in a cell. Applied Imaging’s Ariol and SPOT systems are used for cancer research and to assist in cancer diagnostics. It also markets imaging systems for use in plant and animal genetic research programs. The company sells its products to government and private clinical laboratories, hospital laboratories, research institutions, universities, biotech companies, and pharmaceutical companies through a direct sales force, third-party distributors, and independent sales representatives worldwide. Applied Imaging was founded in 1986 and is headquartered in San Jose, California. As of November 22, 2006, Applied Imaging Corp. is a subsidiary of Genetix Group plc.